In 15th century China two women are born under the same sign, the Metal Snake. But life will take the friends on very different paths.

According to Confucius, 'an educated woman is a worthless woman', but Tan Yunxian born into an elite family, yet haunted by death, separation and loneliness is being raised by her grandparents to be of use. She begins her training in medicine with her grandmother and, as she navigates the male world of medicine, requiring tact and diplomacy, she struggles against the confining world of her class.

From a young age, Yunxian learns about women's illnesses, many of which relate to childbearing, alongside a young midwife-in-training, Meiling. The two girls find fast friendship and a mutual purpose despite the prohibition that a doctor should never touch blood while a midwife comes in frequent contact with it and they vow to be forever friends, sharing in each other's joys and struggles.No mud, no lotus, they tell themselves: from adversity beauty can bloom.

How might a woman like Yunxian break free of tradition, go on to treat women and girls from every level of society, and lead a life of such importance that many of her remedies are still used five centuries later? How might the power of friendship support or complicate these efforts? Lady Tan's Circle of Womenis a captivating story of women helping other women. It is also a triumphant reimagining of the life of a woman who was remarkable in the Ming dynasty and would be considered remarkable today.